HIGH ALCOHOL PREFERRING (HAP) AND LOW ALCOHOL PREFERRING (LAP) RATS SHOW ALTERED PROOPIOMELANOCORTIN (POMC) MESSENGER RNA EXPRESSION IN THE ARCUATE NUCLEUS

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High alcohol preferring (HAP) and low alcohol preferring (LAP) rats show altered proopiomelanocortin (POMC) messenger RNA expression in the arcuate nucleus.

AIMS AND METHODS We have investigated proopiomelanocortin (POMC) and neuropeptide Y (NPY) gene expression in the arcuate nucleus of the hypothalamus comparing high alcohol preference (HAP) rats and low alcohol preference (LAP) rats under basal conditions using in situ hybridization histochemistry. RESULTS A significantly higher expression of POMC mRNA was observed in HAP rats compared with LA...

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Fat-preferring rats consume more alcohol than carbohydrate-preferring rats.

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Drinking of flavored solutions by high preferring (WHP) and low preferring (WLP) alcohol-drinking rats.

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Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats.

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ژورنال

عنوان ژورنال: Alcohol and Alcoholism

سال: 2004

ISSN: 1464-3502,0735-0414

DOI: 10.1093/alcalc/agh076